Pilot Hybrid Effectiveness-Implementation Trials for Mental Health Interventions (R01 Clinical Trial Required)

The National Institutes of Health (NIH) is seeking applications for pilot effectiveness trials focused on optimizing the effectiveness of preventive and therapeutic interventions with previously demonstrated efficacy. The goal of this initiative is to support pilot studies of intervention effectiveness or service delivery approaches that explicitly address whether the intervention engages the target(s)/mechanism(s) presumed to underlie the intervention effects. • The application should focus on mental health interventions. • The study should be a clinical trial. • The applicant should have experience in conducting mental health research. • The application should include a clear description of the intervention and its potential impact. • The applicant should provide a detailed plan for the pilot study, including the study design, methods, and expected outcomes.