Notice of Intent to Award to a Single Source - InChl Trust Membership

The National Center for Biotechnology Information (NCBI) seeks to renew its annual membership with InChl Trust, which provides access to the InChl standard, a critical software for chemistry. The InChl standard enables the determination of small molecule "sameness" and is used by researchers, publishers, pharmaceutical companies, and regulators. The membership is essential for the NCBI Chemistry Program, as it allows for timely updates, involvement in project discussions, and demonstration of leadership in open/FAIR scientific data. • The InChl standard is a digital standard for chemistry, approved by the International Union of Pure and Applied Chemistry (IUPAC). • The standard is used for small molecule "sameness" determination and has no alternative worldwide. • The membership is necessary for the NCBI Chemistry Program to receive timely updates and be involved in project discussions. • The InChl digital standard is a key part of the FAIR data ecosystem, enabling information exchange and interoperability within chemistry and other disciplines.