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U.S. Department Of Defense·Maryland

Notice of Intent to Sole Source - Custom Commercial Aptamer Procurement

Closes 9/1/2026$500k – $2MSole Source
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Description

The U.S. Army intends to award a firm‑fixed‑price sole‑source contract to a single vendor for the custom synthesis, purification, quality‑control, and delivery of DNA, RNA, and peptide aptamers (with optional chemical modifications) in lyophilized form. The work supports diagnostic assay development, biosensor research, and chemical/biological defense missions for the Army’s Chemical Biological Center. The selected contractor must perform denaturing PAGE purification, provide empirical sequence verification via ESI‑MS and 10 % urea gel dPAGE for every delivery, and supply the aptamers on a continuing‑requirement basis.

Attached files

The solicitation documents live at the source — open the bid source above to download them.

Contact

Nicholas Granata Jr.(Contracting Officer)

[email protected]

Key dates

Opened
8/25/2026
Closes
9/1/2026

Last updated

Details

Type
Sole Source
Industry
Chemical Manufacturing
NAICS
541715
Solicitation №
PANAPG-26-P-0000-051608

Budget estimate

$500,000 – $2,000,000

No contract value is disclosed, but custom aptamer synthesis on a continuing‑requirement basis typically involves multiple orders ranging from a few hundred thousand to over a million dollars per year, depending on sequence complexity, quantity, and modification needs. A reasonable estimate for the initial contract period is $500,000 to $2,000,000.

AI estimate from the solicitation

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