The National Institutes of Health (NIH) is seeking applications for the Enhancement and Management of Established Biomedical Data Repositories and Knowledgebases. The purpose of this Notice of Funding Opportunity (NOFO) is to support established biomedical data resources that have demonstrated impact and have potential for continued benefit to the mission of one or more of the NIH Institutes and Centers participating in this announcement. Each application must deliver scientific impact to the communities served, employ and promote good data management practices, engage with the user community and continuously address their needs, and support a process for data life-cycle analysis, long-term preservation, and trustworthy governance.
• The evaluation of the repositories will be based on their usage, utility, impact, quality of data and services, and efficiency of operations, community needs and engagement, trustworthiness of stewardship, and governance.
• The funding opportunity is for a cooperative agreement, and the expected application count is 100.
• The opportunity is open to various applicant types, including for-profit organizations, non-profits, and institutions of higher education.
• The application due date is January 25, 2026.
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