The National Institutes of Health (NIH) is seeking a Multisizer 4e Coulter Counter, which provides improved functionality and analysis capabilities for measuring cell size, counts, and distribution using the Coulter method. The required product should include features such as Coulter method of measurement, automatic aperture blockage detection, code scanner, fluid level monitoring, and selectable stirrer speed and direction. The product should also have a particle sizing range of 0.2-1,600uM, measurement range of 2-80% of aperture size, and measurement linearity of ±1% for diameter and ±3% for volume. The product should be able to provide accurate determination of sample cell number, size, distribution, and concentration, as well as particle count, sizing, and volume distribution data. The product should also have up to 400 size classes or channels, time-stamped pulses up to 525,000 per single analysis, and modes for Total Count, Modal Count, and Volumetric Count.
Some of the key features and requirements of the product include:
• Coulter method of measurement using patented digital pulse processing technology
• Automatic aperture blockage detection and clearing during runs and sample analysis
• Code scanner to scan bar codes on samples, electrolytes, aperture tubes, and sample beakers
• Fluid level monitoring for solutions and waste
• Selectable stirrer speed and direction
• Particle sizing range: 0.2 – 1,600uM
• Measurement range: 2 – 80% of aperture size
• Measurement linearity: Diameter ± 1%, Volume ± 3%
• Dynamic range (accuracy): 1:40 (diameter), 1:64,000 (volume)
• Accurate determination of sample cell number, size, distribution, and concentration
• Particle count, sizing, and volume distribution data, including diameter, volume, and area of number, number percent, number per mL, volume, volume percent, volume per mL, surface area, surface area percent, surface area per mL