Notice of Intent to Sole Source - Chemistry Center for Combating Antibiotic-Resistant Bacteria (CC4CARB)

The National Institutes of Health (NIH) is seeking a contractor to continue the Chemistry Center for Combating Antibiotic-Resistant Bacteria (CC4CARB). The contractor will be responsible for coordinating and conducting the design, synthesis, in vitro testing, and distribution of chemical libraries of discrete natural products and small-molecules with diverse physicochemical properties. The contract will consist of requirements in four key areas: Library Design, Compound Synthesis, Compound Testing, and Compound Management, and includes Project Management of all efforts across these requirements. • The contractor will design, synthesize, and test chemical libraries to target Gram-negative bacterial pathogens and other antibiotic-resistant bacteria. • The contractor will manage all efforts across the four key areas. • The contractor will provide project management services to ensure the successful completion of the contract.