Description
The Centers for Disease Control and Prevention (CDC) is inviting research proposals to study risk factors for Amyotrophic Lateral Sclerosis (ALS). The proposals should focus on identifying potential environmental and other associated risk factors for ALS in humans and characterizing how or why these risk factors could be associated with or contribute to the etiology, progression, and pathophysiology of ALS. The proposed research should produce outcomes that will help the CDC better understand the etiology and epidemiology of ALS, prioritize topics for future research initiatives, and develop new CDC/ATSDR National ALS Registry risk factor surveys for persons with ALS. Some of the key areas of focus include:
• Military service
• Contact sports
• Traumatic brain injury
• Neuroinflammation
• Infectious agents
There are four funding options included in this NOFO:
• Option A - Support research with strong existing evidence
• Option B - Support new and exploratory research on ALS risk factors
• Option C - Understand ALS risk in affected populations
• Option D - Analyze biological samples from the Guamanian ALS cluster