Description
The National Institute on Neurological Disorders and Stroke (NINDS) intends to modify the multiple-award Indefinite Quantity Indefinite Delivery (IDIQ) contracts under the Pharmacology and Toxicology for Therapeutics Program (PTTP). The goal of the PTTP is to assess the pharmacokinetics, toxicology, and safety of promising candidates to support their eventual use as therapeutics. The contract will serve as part of the NIH Blueprint Neurotherapeutics Network and will also be utilized for individual development projects outside of the Blueprint Network.
The key services to be performed may include:
• Development and validation of analytical methods for quantitating drug/biologic concentrations
• In vivo pharmacokinetic studies
• Preclinical acute toxicity evaluations
• Subacute, subchronic, and/or long-term toxicity evaluations
• Safety Pharmacology Studies
• Genotoxicity assessments
• In vitro predictive ADMET assays
Attached files
Contact
Sneha Singh(Contacting Officer)