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U.S. Department Of Health And Human Services·Maryland

IVM-CMS Platform: all-in-one Intravital Microscope (IVM) system

Closes 9/9/2026$500k – $2MRequest for Information
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Description

The National Institutes of Health (NIH) – National Environmental Health Sciences (NIEHS) is issuing a Sources‑Sought notice to identify small‑business firms capable of delivering a turnkey, all‑in‑one intravital microscopy (IVM) platform. The system must integrate confocal/two‑photon lasers, motion‑compensation hardware, and dedicated imaging software to enable real‑time, high‑resolution imaging of live animal tissues at cellular and sub‑cellular levels. The award will be a firm‑fixed‑price contract with a three‑year warranty period, installed at the NIEHS facility in Research Triangle Park, NC. Responses are due September 9 2026. • Turnkey IVM‑CMS platform (hardware + software) for live‑animal imaging • Must include confocal/two‑photon microscopy, motion compensation, and imaging software (IVM Engine & Studio) • Installation and three‑year warranty required; performance at NIEHS, RTP, NC • Small‑business set‑aside; capability statements limited to 7 pages • Submission via email to Luz Casey by 9:00 am EST, September 9 2026

Attached files

Contact

Luz Casey(Program Specialist)

[email protected]

Key dates

Opened
9/5/2026
Closes
9/9/2026
Duration
3 years

Last updated

Details

Type
Request for Information
Industry
Manufacturing
NAICS
334516
Solicitation №
PCA-NIEHS-04774

Budget estimate

$500,000 – $2,000,000

The IVM‑CMS platform is a high‑end scientific imaging system typically priced between half a million and a few million dollars, depending on laser configurations, software licensing, installation, and warranty terms. Considering the need for confocal/two‑photon lasers, motion‑compensation hardware, and a three‑year service warranty, a reasonable estimate is $500,000 – $2,000,000. Larger configurations with multiple imaging modalities could push the upper bound higher, while a basic single‑laser setup might sit near the lower bound.

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