NIAID SBIR Phase II Clinical Trial Implementation Cooperative Agreement (U44 Clinical Trial Required)

This Notice of Funding Opportunity (NOFO) encourages Small Business Innovation Research (SBIR) grant applications from small business concerns (SBCs) that propose to implement investigator-initiated clinical trials related to the research mission of the NIAID. This program provides support for hypothesis-driven, milestone-driven clinical trials. Although clinical trials not considered high-risk may be proposed, this program encourages high-risk clinical studies. Key aspects of the opportunity include: • High-risk clinical studies are encouraged, but do not imply human subject or patient risk • Mechanistic studies are also encouraged and may be proposed under this program • The program provides support for hypothesis-driven, milestone-driven clinical trials • Small business concerns (SBCs) are eligible to apply • Non-domestic (non-U.S.) entities are not eligible to apply