Chemical Countermeasures Research Program (CCRP) Initiative: Basic Research on The Deleterious Effects of Acute Exposure to Ultra-Potent Synthetic (UPS) Opioids (R01 Clinical Trial Not Allowed)

This notice of funding opportunity (NOFO) will support research towards understanding and mitigating the deleterious effects of acute exposure to Ultra-Potent Synthetic (UPS) opioids (e.g., fentanyl, carfentanil, nitazenes) and their combinations (fentanyl and xylazine). The research will focus on the persistent and/or delayed pathophysiological effects after acute exposure to such agents. • The opportunity is open to various applicant types, including city or township governments, special district governments, nonprofits, and for-profit organizations. • The estimated funding for this opportunity is $300,000. • The application deadline is November 18, 2027. • The opportunity is sponsored by the National Institutes of Health (NIH). • The research will be supported through a grant funding mechanism.