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U.S. National Institutes of Health·United States of America

Silvio O. Conte Centers for Basic Neuroscience or Translational Mental Health Research (P50 Clinical Trial Optional)

Closes 6/8/2026$800k – $2MGrants Notice
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Description

The National Institute of Mental Health (NIMH) is soliciting multi‑institutional, interdisciplinary research teams to establish Silvio O. Conte Centers focused on basic neuroscience or translational mental‑health research. The program seeks high‑risk, high‑impact projects that (a) advance fundamental brain‑behavior science, (b) bridge basic and clinical neuroscience for severe mental illnesses, and (c) elucidate neurodevelopmental trajectories of psychopathology. Applications must follow the P50 Specialized Center guidelines, include a Data Management and Sharing Plan, and be submitted through the NIH eRA Commons by the due date. Funding is limited to $2 million per award, with an anticipated start in April 2027. The award is a cooperative agreement (though noted “Not Applicable”) and will require annual progress reporting (RPPR) and financial statements. • Target audience: Universities, research institutes, and eligible non‑profits with expertise in neuroscience, psychiatry, or translational mental‑health research. • Funding mechanism: P50 Specialized Center grant (research‑center). • Estimated award ceiling: $2 M (no minimum). • Submission portal: NIH ASSIST/eRA Commons (eRA Service Desk contact). • Key dates: Open Sep 15 2026; due May 25 2028; award expected Apr 1 2027; project start Apr 1 2027. • Required documents: Multi‑project application, DMS plan, budget, biosketches, etc. • Eligibility: U.S. public or private institutions (state, local, tribal, higher education, nonprofits, for‑profit); foreign entities ineligible.

Attached files

Contact

Suzanne T. Garcia, Ph.D.

[email protected]

(301) 827-1366

Key dates

Opened
9/12/2025
Closes
6/8/2026
Projected award
4/1/2027
Duration
4 years

Last updated

Details

Type
Grants Notice
Industry
Healthcare and Medical Services
NAICS
541715
Solicitation №
PAR-27-127

Budget estimate

$800,000 – $2,000,000

The award ceiling is listed as $2,000,000, which represents the maximum NIH will allocate to a single Conte Center. Historically, Conte Centers receive between $0.5 M and the full $2 M depending on the scope, number of sub‑projects, and the size of the research team. Assuming a competitive, well‑structured proposal, a realistic funding range would be roughly $800,000–$2,000,000. Factors influencing the final amount include the number of collaborating institutions, the inclusion of clinical trial components, and the breadth of the translational plan.

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