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U.S. Department Of Health And Human Services·Maryland

Transcriptomic characterization of plasma exosomes

Closes 8/31/2026$100k – $300kRequest for Quotation
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Description

This solicitation seeks a vendor to supply a suite of New England Biolabs (NEB) consumables and reagents required to process 650 plasma exosomal RNA samples for next‑generation sequencing. The Center for Research on Genomics and Global Health will use these kits to generate Illumina‑compatible libraries, deplete ribosomal RNA, and produce multiplexed sequencing libraries, supporting a one‑year, one‑time‑use project aimed at characterizing plasma exosome transcriptomes for biomarker discovery in cardiometabolic disease research. • Provide multiple NEBNext Multiplex Oligos for Illumina (sets 1‑4) • Supply NEBNext rRNA Depletion Kit v2 (Human/Mouse/Rat) • Deliver NEBNext Ultra II Directional RNA Library Prep kits • All products must be stored and used per manufacturer specifications • Delivery/shipping updates required; no inspection/acceptance criteria listed.

Attached files

Contact

Ava Miller

[email protected]

Key dates

Opened
8/20/2026
Closes
8/31/2026
Duration
1 year

Last updated

Details

Type
Request for Quotation
Industry
Healthcare and Medical Services
NAICS
423450
Solicitation №
NHGRI-09000

Budget estimate

$100,000 – $300,000

The solicitation does not disclose a contract value. Based on typical pricing for NEB kits (e.g., a multiplex oligo set ≈ $1,200, rRNA depletion kit ≈ $1,500, Ultra II library prep kit ≈ $2,000) and the quantities required (multiple sets of each), the total cost is likely in the low‑hundreds of thousands. A reasonable estimate would be between $100,000 and $300,000, depending on negotiated unit prices, shipping, and any ancillary services.

AI estimate from the solicitation

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