The Brookhaven National Laboratory (BNL) is seeking information from qualified vendors regarding advanced confocal laser scanning and super-resolution optical microscopy systems. The desired system should combine confocal, FLIM, and STED nanoscopy modalities in a unified platform, provide high sensitivity for live-cell imaging and long-term time-lapse studies, and offer tunable excitation across a broad spectral range. The system should also integrate automation features, intuitive software, and full compatibility with standard imaging analysis workflows.
Key features of the system include:
• High-speed beam routing for multicolor excitation switching within microseconds
• Spectral detection range of around 410–850 nm, with up to five simultaneous, tunable detection channels
• Photon detectors with high efficiency, around 50% @ 500 nm
• Ability to perform lifetime-based contrast and FRET measurements
• Software platform for image acquisition and analysis, including automation, alignment, calibration, and data processing
• Compatibility with standard analysis tools (ImageJ/Fiji, MATLAB, Python)
The laboratory is seeking expressions of interest from firms regarding the Advanced Confocal and Super-Resolution Microscopy System, and vendors are encouraged to respond to a set of questions in addition to providing their standard technical documentation and brochures.
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