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U.S. Department Of Energy·New York

Request for Information (RFI) Advanced Confocal and Super-Resolution Microscopy System

Closes 1/30/2026$500k – $2MRequest for Information
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Description

The Brookhaven National Laboratory (BNL) is seeking information from qualified vendors regarding advanced confocal laser scanning and super-resolution optical microscopy systems. The desired system should combine confocal, FLIM, and STED nanoscopy modalities in a unified platform, provide high sensitivity for live-cell imaging and long-term time-lapse studies, and offer tunable excitation across a broad spectral range. The system should also integrate automation features, intuitive software, and full compatibility with standard imaging analysis workflows. Key features of the system include: • High-speed beam routing for multicolor excitation switching within microseconds • Spectral detection range of around 410–850 nm, with up to five simultaneous, tunable detection channels • Photon detectors with high efficiency, around 50% @ 500 nm • Ability to perform lifetime-based contrast and FRET measurements • Software platform for image acquisition and analysis, including automation, alignment, calibration, and data processing • Compatibility with standard analysis tools (ImageJ/Fiji, MATLAB, Python) The laboratory is seeking expressions of interest from firms regarding the Advanced Confocal and Super-Resolution Microscopy System, and vendors are encouraged to respond to a set of questions in addition to providing their standard technical documentation and brochures.

Attached files

Contact

Mark Brock(Subcontracts Supervisor)

[email protected]

(631) 344-2713

Key dates

Opened
12/31/2025
Closes
1/30/2026

Last updated

Details

Type
Request for Information
Industry
Healthcare and Medical Services
NAICS
518210
Solicitation №
BSA-RFI-473012

Budget estimate

$500,000 – $2,000,000

The budget for this opportunity is difficult to estimate because it is a Request for Information (RFI) and not a solicitation for a contract award. However, based on the complexity and sophistication of the desired system, it is likely that the budget will be in the range of $500,000 to $2 million. This estimate is influenced by the cost of similar microscopy systems on the market, as well as the potential for customization and integration with existing laboratory equipment.

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