TECHNOLOGY LICENSING OPPORTUNITY: Thermostable GlowTag (YFAST)

The Los Alamos National Laboratory is offering a technology licensing opportunity for a thermostable GlowTag (YFAST) that enables rapid, high-throughput screening of enzymes at high temperatures. The technology has various applications in industries such as biofuels, waste management, and chemical manufacturing. The key advantages of this technology include improved screening accuracy, expanded access to thermostable enzymes, and reduced storage and operational costs. • Enables rapid, high-throughput screening at high temperatures • Introduces a thermostable fluorogenic reporter that provides an optical response • Improves screening accuracy by using direct selection rather than elimination-based methods • Expands access to thermostable enzymes by allowing common mesophilic enzymes to be engineered for heat resistance • Reduces storage and operational costs by producing enzymes that remain stable without refrigeration