Two-photon Microscope for Calcium Imaging of Cortical Activity in Behaving Mice

The contract is for the provision of a two-photon fluorescence microscope system for in vivo imaging of neural circuit activity during behavior. The system will support research on neural mechanisms of decision-making, sensory processing, and generalization across cortical areas, providing cellular-resolution recordings in behaving animals. The contract was awarded to Thoralabs, Bruker, and Nikon, with total prices of $392,920.42, $386,370.00, and $633,150.00 respectively. • The contract is an Invitation to Bid (ITB) with the solicitation number ITB 6774-3. • The bid posting date was 10/30/2025 3:00 PM EDT and the bid submission date was 11/14/2025 3:00 PM EST. • The contract is for the provision of a two-photon fluorescence microscope system. • The system will support research on neural mechanisms of decision-making, sensory processing, and generalization across cortical areas. • The contract was awarded to three vendors: Thoralabs, Bruker, and Nikon.