Single Source for Continuation of the Accelerating Medicines Partnership (AMP) in Common Metabolic Diseases (CMD) Knowledge Portal (U01 Research Project (Cooperative Agreement) Clinical Trial not allowed)

This non-competitive Notice of Funding Opportunity (NOFO) is intended to fund a single award to the current awardee institution of the Accelerating Medicines Partnership in Common Metabolic Diseases Knowledge Portal (AMP CMD KP), the Broad Institute, Inc. The AMP CMD program is a collaborative partnership between the NIH, pharmaceutical companies, and nonprofit organizations to develop new models for identifying and validating promising biological targets to serve as biomarkers and/or for drug discovery. The goal of this NOFO is to provide funds to the AMP CMD KP to continue the development and maintenance of the web portal and underlying, curated knowledge base. • The AMP CMD KP will continue its expansion of its datasets and traits, import additional data types, deploy additional analytical and visualization tools, and increase its utility to a more diverse user base. • The application will be peer-reviewed and if it is not a meritorious application, it will not be funded. • The NIDDK Program Official or their Project Scientist or Project Coordinator will serve as the Executive Secretary and/or NIDDK program representative on the DSMB/OSMB. • A Steering Committee organized by the study investigator(s) will be the main governing body of the study.