The U.S. Food and Drug Administration (FDA) is seeking information from potential vendors about their ability to provide an Agilent Cytation 9 Cell Imaging Multimode Reader or equivalent instrument. The system should have automated high-throughput image acquisition and analysis capabilities, configurable upright and inverted microscopy, and filter- and monochromator-based multimode microplate reading. The system will be used for screening applications, development, evaluation, and validation of New Approach Methodologies (NAMs). Key features include:
• Automated digital microscopy and multimode detection in one system
• Compatibility with 6 to 384-well microplates, microscope slides, and counting chambers
• Fluorescence, brightfield, color brightfield, phase contrast, and high-contrast brightfield imaging modes
• Ability to integrate with available automated incubator for live cell imaging workflows
• End-point, time lapse, Z-stack, and montage imaging methods
The FDA is seeking capability statements from vendors that can provide this system, including information about their company, past performance, and technical capabilities.
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