Cooperative Program for Modeling Clinical Transplantation

The National Institute of Allergy and Infectious Diseases (NIAID) is seeking applications for the Cooperative Program for Modeling Clinical Transplantation. This program aims to support innovative and clinically translatable in-vitro and in-vivo systems to model local and systemic immune responses, with the goal of promoting translation of new therapies to clinical practice. The program will support new approach methods (NAMs) and/or refined mouse models that address known obstacles to clinical translation and reduce reliance on nonhuman primates. Some key aspects of this opportunity include: • Emphasis on data sharing to facilitate reproducibility and establishment of standards and best practices • Requirement for applicants to propose models designed to overcome known obstacles to clinical translation • Focus on reducing reliance on nonhuman primates • Goal of promoting translation of new therapies to clinical practice