HGMD (Human Gene Mutation Database) MySQL software renewal

The National Institutes of Health intends to award a Firm-Fixed-Price purchase order to Qiagen, LLC for the HGMD (Human Gene Mutation Database) MySQL software renewal. The HGMD software is integrated into the exome analysis pipeline and is necessary for determining disease-causing mutations. Qiagen, LLC is the manufacturer and the only known responsible source that can provide the item that meets the standards. • The software provides comprehensive data on human inherited disease mutations. • It enables quick access to detailed reports for inherited disease mutations. • It allows for verification of observed mutations and analysis of candidate genes for disease linkage and predisposition. • The software is a unique resource that will enable the UDP laboratory to quickly prioritize mutations from whole exome or whole genome sequencing.