Single Source: Chronic Kidney Diseases of UnceRtain Etiology (CKDu) in Agricultural Communities (CURE) Research Consortium- Renal and Environmental Science Core (U01-Clinical Trial Not Allowed)

The National Institutes of Health is seeking applications for a single source grant to support the continuation of the Consortium to Study Chronic Kidney Disease of UnceRtain Etiology (CKDu) in Agricultural Communities (CURE). The grant will focus on the Renal and Environmental Science Core, which will provide support and leadership in discovery science. The consortium aims to understand the etiologies of CKDu, the exposures that initiate and affect progression of tubulointerstitial kidney disease, potential therapeutic targets, and future opportunities for public health interventions. • The grant will support research on CKDu, which causes kidney failure in rural areas of many Low and Middle Income Countries. • The consortium will include Field Epidemiology Sites, a Renal and Environmental Science Core, and a Data Coordinating Center. • The grant will provide an estimated $1,750,000 in funding. • The project will serve as a resource for ancillary studies. • The grant is a single source Notice of Funding Opportunity (NOFO) that will invite application(s) from eligible organizations to apply.