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U.S. Department Of Health And Human Services·Maryland

Pharmacogenomic Analysis of Participants Enrolled in the STAR-B Randomized Clinical Trial of Semaglutide for Alcohol Use Disorder

Closes 9/15/2026$3M – $12MSole Source
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Description

The National Institute on Drug Abuse (NIDA) is issuing a non‑competitive, sole‑source Notice of Intent to award a purchase order to Novogene Corporation, Inc. for comprehensive human whole‑genome sequencing and bio‑informatics services. The work supports the STAR‑B randomized clinical trial evaluating semaglutide for Alcohol Use Disorder. Novogene will receive biospecimens, perform DNA extraction (if needed), conduct quality control, execute genome‑wide genotyping/sequencing, process raw data, and deliver final datasets with full chain‑of‑custody documentation. The effort must align with the parallel STAR‑T trial at Oklahoma State University to ensure methodological consistency across both studies. • Scope: DNA extraction, QC, whole‑genome sequencing or genotyping, bio‑informatic processing, data delivery, and documentation. • Deliverables: Raw sequencing files, processed variant calls, QC reports, sample‑tracking records. • Value: NAICS size standard $19 M; contract likely under the simplified acquisition threshold. • Deadline for responses: September 15, 2026 (3:00 PM ED). • Required: Active SAM registration, UEI, TIN, size‑standard certification. • Location: Services performed by Novogene (provider) with specimen handling by NIDA.

Attached files

Contact

Zachary Fetters

[email protected]

(240) 236-9291

Key dates

Opened
9/8/2026
Closes
9/15/2026

Last updated

Details

Type
Sole Source
Industry
Healthcare and Medical Services
NAICS
541380
Solicitation №
NOI-PCA-NIDA-09054

Budget estimate

$3,000,000 – $12,000,000

The solicitation cites a $19 million small‑business size standard, indicating the total contract ceiling could be up to that amount. Similar federal whole‑genome sequencing contracts for large clinical trials typically range from a few million dollars to the high‑single‑digit millions, depending on sample volume and data‑processing depth. Assuming a moderate sample set (several hundred participants) and comprehensive bio‑informatics, a realistic award value would likely fall between $3 M and $12 M. Factors influencing the final figure include the number of genomes sequenced, depth of coverage, and any additional custom analyses requested by NIDA.

AI estimate from the solicitation

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